Evaluating biomarkers in melanoma

Evaluating Biomarkers in Melanoma

The incidence of cutaneous melanoma has more than doubled over the last decades making it one of the fastest rising cancers worldwide. Improved awareness and early detection of malignant moles now permit earlier diagnosis aiming to decrease the likelihood of recurrence. However, it is difficult to identify those patients initially diagnosed with localized melanoma who subsequently develop metas...

Biomarkers in melanoma

Biomarkers are tumour- or host-related factors that correlate with tumour biological behaviour and patient prognosis. High-throughput analytical techniques--DNA and RNA microarrays--have identified numerous possible biomarkers, but their relevance to melanoma progression, clinical outcome and the selection of optimal treatment strategies still needs to be established. The review discusses a pos...

Prognostic Biomarkers in Melanoma

Biomarkers are tumouror host-related factors that correlate with tumour biological behaviour and patient prognosis. Modern analytical techniques have identified numerous possible biomarkers, but their relevance to melanoma progression, clinical outcome and the selection of optimal treatment strategies still needs to be established. In this review, we discuss common predictive biomarkers of mela...

Identification of key genes in melanoma metastasis and investigating their potential as biomarkers

Background and Aim: Considering the high global incidence of skin cancer and the high mortality rate caused by melanoma, it is important to identify the genes involved in this disease and predict effective drugs. Therefore, in this study, we have identified and investigated the expression level of effective and key genes in melanoma metastasis, as well as investigating their diagnostic potentia...

Emerging GM3 Regulated Biomarkers in Malignant Melanoma